Journal of Medicinal and Chemical Sciences

Efficacy of Ultrasound Guided Bilateral Subcostal Tap Block and Ultrasound Guided Celiac Plexus Block Using a Novel Supra Celiac Approach for Anaesthesia during Open Palliative Feeding Jejunostomy- A feasibility Study

Surya .R; Priya .H; B.M. Sathesh Kumar; Ameerunnisha Begum; Yachendra V.S.G; Lakshmi .R

Volume 6, Issue 12 , December 2023, , Pages 2884-2895

https://doi.org/10.26655/JMCHEMSCI.2023.12.3

Abstract

Background: General or Regional anaesthesia are the most common anaesthetic techniques practiced for open palliative feeding jejunostomy (PFJ) for advanced esophageal cancer. However, ... Read More

The Ethanolic Extract of Basic Leaves (Ocimum basilicum) Effect on Expression of Follicle Stimulating Hormone Receptors (FSHr) and Folliculogenesis in Female Mice Model Endometriosis

Fadhilatul Karimah; Ashon Sa’adi; Widjiati Widjiati

Volume 6, Issue 12 , December 2023, , Pages 2896-2905

https://doi.org/10.26655/JMCHEMSCI.2023.12.4

Abstract

Background: Endometriosis is a tissue disease similar to the endometrial lining, either glands or stroma that grows outside the uterus which is one of the causes of infertility due ... Read More

Evaluation of Cuff Pressure Monitoring in Attenuating Post-Operative Laryngo-Tracheal Complications in Adults Due to Oro-Tracheal Intubation: A Prospective Randomized Controlled trial

Yachendra V.S.G; S. Abirami; Ameerunnisha Begum; Surya .R; Lakshmi .R

Volume 6, Issue 12 , December 2023, , Pages 2906-2912

https://doi.org/10.26655/JMCHEMSCI.2023.12.5

Abstract

Introduction: The most common laryngo-tracheal complaints following General anesthesia with tracheal intubation in the postoperative period are sore throat and hoarseness of voice with ... Read More

Evaluating the Effectiveness of Ketamine in reducing Postoperative Nausea and Vomiting in Adults after General Anaesthesia: A Prospective Randomized Controlled Trial

Yachendra V.S.G; Girimurugan .N; Ameerunnisha Begum; Anand. S; Surya. R; Lakshmi. R

Volume 6, Issue 12 , December 2023, , Pages 2934-2940

https://doi.org/10.26655/JMCHEMSCI.2023.12.8

Abstract

Background: Postoperative Nausea and Vomiting (PONV) is defined as any nausea, retching or vomiting occurring during the first 24-48 hours after surgery with a reported incidence of ... Read More Background: Postoperative Nausea and Vomiting (PONV) is defined as any nausea, retching or vomiting occurring during the first 24-48 hours after surgery with a reported incidence of 30% in all post-surgical patients and up to 80% in high risk groups especially in laparoscopic surgeries under general anaesthesia. Many drugs have been tried and tested for abolishing PONV. We evaluated the efficacy of low dose ketamine in decreasing the incidence and severity of PONV following elective laparoscopic surgeries under general anaesthesia.Method: 40 patients belonging to American Society of Anaesthesiologists Physical status I who were scheduled for elective laparoscopic surgeries under general anaesthesia were recruited and randomized into two groups Group A and Group B. Standard protocol for general anaesthesia were followed for all patients. Patients in Group A received Intravenous ketamine of 0.2mg/kg and Patients in Group B received the saline control half an hour before extubation. The incidence and severity of PONV, number of rescue drug administration, and side effects were recorded for first 24 postoperative hours in different time periods.Results: Demographic profile were comparable among the groups. The incidence and severity of postoperative nausea were significantly higher in Group B when compared to Group A for the first 6 postoperative hours (p<0.05) and thereafter, it was comparable between the groups. The incidence of postoperative vomiting was significantly higher in Group B when compared to Group A for the first 2 postoperative hours (p<0.04), and then it was comparable between the groups. The number of rescue medications were significantly higher in Group B when compared with Group A. No complications were noted.Conclusion: Low dose intravenous ketamine (0.2 mg/kg) administered as a single bolus reduced the incidence and severity of postoperative nausea and vomiting in adults undergoing laparoscopic surgeries under general anaesthesia without any complications.

Correlation of Severity of Preoperative Stopbang Scores and Incidence of Postoperative Pulmonary Complications in Adults Undergoing Elective Surgeries under General Anesthesia - a Prospective Observational Study

Ameerunnisha Begum; Priya. H; B.M.Sathesh Kumar; Sai Vaishnavi Chowdary.R; Surya. R; Lakshmi. R

Volume 6, Issue 12 , December 2023, , Pages 3012-3018

https://doi.org/10.26655/JMCHEMSCI.2023.12.16

Abstract

Introduction: Obstructive sleep apnoea (OSA) is a medical disorder and when non-diagnosed precipitates the risk for post-operative pulmonary complications (POPC). STOPBANG score is ... Read More

Evaluation of Malnutrition by Skinfold Thickness Measurement and SGA-DMS among Haemodialysis Patients: A Cross-Sectional Study

Jagadeesan M; Sreedhar S; Vijayakumar T M

Volume 6, Issue 12 , December 2023, , Pages 3044-3056

https://doi.org/10.26655/JMCHEMSCI.2023.12.20

Abstract

Protein-energy malnutrition occurs in a large portion of patients with chronic renal failure. It leads to the consequences of various factors like hormonal imbalance, reduced food intake ... Read More

An Overview and Comparison of Regulatory Pathways and Guidelines for Pediatric Study Plans in the US and EU

Chinmayi C S; Pratheksha S; Lavanya Mude; Madhukiran Parvathaneni; Kalaivanan R; Veera Venkata Satyanarayana Reddy Karri

Volume 6, Issue 12 , December 2023, , Pages 3057-3071

https://doi.org/10.26655/JMCHEMSCI.2023.12.21

Abstract

Pediatric research is critical to the development of safe and effective treatments for children. The US Food and Drug Administration (FDA) and the European Union (EU) have produced ... Read More

Formulation of Aromatherapy Massage Oil from Lavender (Lavandula Angustifolia), Chamomile (Matricaria Recutita), and Petitgrain (Citrus Aurantium) for Stress Relief

Burhan Ma’arif; Ersi Nurfadhilah; Faisal Akhmal Muslikh; Agnis Pondineka Ria Aditama; Arief Suryadinata; Iwal Reza Ahdi; Maximus Markus Taek; Novia Maulina

Volume 6, Issue 12 , December 2023, , Pages 3078-3086

https://doi.org/10.26655/JMCHEMSCI.2023.12.23

Abstract

Stress is non-specific response of the body to the demands placed on it, which have an impact on anxiety, depression, and muscle pain. The use of synthetic drugs causes side effects ... Read More

Bidara Upas (Merremia mammosa Hall) Antiviral Activity Against SARS-COV-2

Neny Purwitasari; Mangestuti Agil; Siswandono Siswodihardjo; Reviany Vibrianita Nidom

Volume 6, Issue 12 , December 2023, , Pages 3149-3158

https://doi.org/10.26655/JMCHEMSCI.2023.12.28

Abstract

The world was startled in December 2019 by the emergence of an unprecedented pneumonia outbreak in Wuhan, China, with an unknown cause. However, on January 7, 2020, researchers successfully ... Read More

Virgin Coconut Oil Supplementation as Ulcerative Colitis Prevention, Does it work? Clinical Correlation

Ni Made Rika Trismayanti; Kusworini Handono; Dian Handayani; Umi Kalsum

Volume 6, Issue 12 , December 2023, , Pages 3178-3187

https://doi.org/10.26655/JMCHEMSCI.2023.12.31

Abstract

Background and objectives: Ulcerative colitis (UC) is an inflammatory disease of the large intestine characterized by diffuse mucosal damage accompanied by ulceration. UC is associated ... Read More

The Nutritional Variation Next to COVID-19: A Cross-Sectional Study

N Juni Triastuti

Volume 6, Issue 12 , December 2023, , Pages 3188-3197

https://doi.org/10.26655/JMCHEMSCI.2023.12.32

Abstract

The COVID-19 pandemic has been going on since the end of 2019 until now and many positive residents have been confirmed to be suffering from symptoms of COVID-19. However, there is ... Read More

Effectiveness of Cognitive Behavioral Therapy for Suicidal Attempt

Ahmed Ali Rasool; Abdulqader Hussein Hmad

Volume 6, Issue 12 , December 2023, , Pages 3210-3220

https://doi.org/10.26655/JMCHEMSCI.2023.12.34

Abstract

Background and Objective: Due to the increasing focus of new therapies on immediate and short-term interventions, Cognitive-Behavioural Therapy (CBT) has been designed to decrease suicidality ... Read More

Emergency Medical Care Functioning During COVID-19 Pandemic in Eastern Europe

Oleksandr Knigavko; Nadiia Baranova; Ievgen Bausov; Maryna Dolzhenko; Nataliia Lantukhova

Volume 6, Issue 11 , November 2023, , Pages 2588-2599

https://doi.org/10.26655/JMCHEMSCI.2023.11.3

Abstract

Objective: The objective of this study is to examine the challenges faced by treatment organizations and assess the current state of emergency medical care facilities in Poland and ... Read More

Investigating the Effect of E-Learning with a Blended Approach on the Rate of Learning in Nursing Students during COVID-19 Pandemic

Saba Karimi; Mehrdad Derakhshan; Fatemeh Jabinian; Amirhossein Tondro

Volume 6, Issue 11 , November 2023, , Pages 2620-2627

https://doi.org/10.26655/JMCHEMSCI.2023.11.6

Abstract

Introduction: Coronavirus 2019 (COVID-19) is a highly infectious disease. It has spread throughout the world in a short period and this widespread outbreak has caused many problems ... Read More

Radiographic Findings of Lung CT Scans of COVID-19 Patients: Delta and Omicron Variants

Somayeh Mehrpour; Reihane Tabaraii; Hassan Safdari; Mohammad Aghaali; Mansoureh Shakeri; Alireza Shahhamzeh; Mahnaz Rahimi Jafari

Volume 6, Issue 11 , November 2023, , Pages 2672-2678

https://doi.org/10.26655/JMCHEMSCI.2023.11.11

Abstract

Objective: The present study was designed with the aim of comparing the radiological findings of the CT scan of the lungs of patients with Delta and Omicron variants of COVID-19 hospitalized ... Read More Objective: The present study was designed with the aim of comparing the radiological findings of the CT scan of the lungs of patients with Delta and Omicron variants of COVID-19 hospitalized in the intensive care unit.Methods: This was a retrospective comparative study conducted during the fifth peak of COVID-19 in Iran, August to November 2021 (the predominance of Delta variant) and March to April 2022 (the predominance of Omicron variant) in Qom, Iran. Radiologic findings of lung CT scans reported by a single radiologist were compared between these two cohorts. To analyze the collected data, SPSS version 22 statistical software is used through chi-square or fisher exact test, independent t-test, and Mann-Whitney test. A p-value of lower than 0.05 was considered as statistically significant.Results: The total number of 50 patients in Delta (mean age of 58.68±14.77 years, 56% male) and 46 patients in Omicron (mean age of 70.45±18.02 years, 47% male) periods were included in study. Lesions of Right middle lobe (RML), left upper lobe (LUL), and Lingual lobes were more common in Delta period than Omicron (P<0.05). GGOs were more common in Delta period than in the Omicron ‎ (P=0.013). There were no Unilateral GGOs during the Delta period, while 9 of 32 (28.1%) patients having GGO lesions in Omicron era had unilateral ones (P<0.001). Peripheral lesion was not differentiating Omicron from Delta. Crazy Pavings, Parenchymal bands, Halo signs, and Pleural effusions were more common in omicron period than in the Delta (P<0.05). Total Chest CT severity score was statistically higher in Delta period (22.75±5.24 units) than Omicron period (13.97±9 units).Conclusion: There were the significant differences in the radiologic characteristics between the two variants. This study suggests that with evolving the virus variants, while severity of lung involvement has decreased, GGOs of COVID-19 might have tended to manifest as unilateral lesions with more specific radiographic features.

Comparative Study Between Cuff Leak Test and Laryngeal U/S for Detection of Post Extubation Oedema in Prone Position Patient with General Anesthesia

Abdel Wahab Abdelsattar Saleh Mohammad; Maher A sheriff; Yara Ayman Iskandarani; Wael Mohammed Mossa; Mohamrd Hamdi Alqassas

Volume 6, Issue 11 , November 2023, , Pages 2686-2698

https://doi.org/10.26655/JMCHEMSCI.2023.11.13

Abstract

Background: Endotracheal intubation is a routine procedure in the ICU that may save a patient's life. The stridor probability after extubation increases with a smaller cuff-leak volume. ... Read More

Curcuma Longa May Prevent Endothelial Dysfunction in Rattus Norvegicus Exposed by Soot Particulate through Changes of OxLDL and eNOS Levels

Muhammad Aminuddin; Djanggan Sargowo; Teguh Wahju Sardjono; Widjiati Widjiati

Volume 6, Issue 11 , November 2023, , Pages 2785-2792

https://doi.org/10.26655/JMCHEMSCI.2023.11.23

Abstract

The purpose of this study is to prove the efficacy of Curcuma longa (turmeric) extracts against soot (carbon black)-exposed rats with Ox-LDL and eNOS levels. A total of 30 rats were ... Read More

Levels of Zinc and Iron Serum in Children with Febrile Seizures: Systematic Review and Meta-Analysis

Savitri Kuntari; Rifah Zafarani Soumena; Melinda Masturina; Ratih Kumala Sari; Sunny Mariana Samosir; Riza Noviandi; Citrawati Dyah Kencono Wungu; Prastiya Indra Gunawan

Volume 6, Issue 11 , November 2023, , Pages 2812-2823

https://doi.org/10.26655/JMCHEMSCI.2023.11.26

Abstract

Background: Febrile seizures are common in the paediatric population; the frequency of febrile seizures is significantly influenced by hereditary variables. Other variables, such as ... Read More

The Effectiveness of Massaging, Swaddling, and Reflexology Intervention in Mothers’ Practices Regarding Infantile Colic

Gulala K. Azeez; Abass Al-Rabati; Shukir S. Hasan

Volume 6, Issue 10 , October 2023, , Pages 2273-2281

https://doi.org/10.26655/JMCHEMSCI.2023.10.2

Abstract

Background and objectives: During the first few months of a baby's life, the parents should deal with terrible condition of infantile colic, in which the infantile cries, groans, or ... Read More

Prevalence of Entamoeba Histolytica and Giardia Lamblia in Children Visiting to Heevi Pediatric Hospital in Dohuk City, Kurdistan Region, Iraq

Haveen Khalid Hasan; Souzan Hussain Eassa; Haval Mohammed Khalid

Volume 6, Issue 10 , October 2023, , Pages 2292-2299

https://doi.org/10.26655/JMCHEMSCI.2023.10.4

Abstract

Entamoeba histolytica and Giardia lamblia are considered as two of the most widely distributed gastrointestinal protozoan parasites in the world, especially in underdeveloped nations, ... Read More

Prophylactic Low Dose Intravenous Ketamine Infusion in Prevention of Intraoperative and Postoperative Shivering after Spinal Anesthesia in Adults Scheduled for Abdominal and Lower Limb Surgeries- A Prospective Randomized Controlled Trial

Surya R; Vaishali A.S; Tasneem Fathima Ahmed; Prem Chandar L.K; Yachendra V.S.G; Lakshmi R

Volume 6, Issue 10 , October 2023, , Pages 2300-2309

https://doi.org/10.26655/JMCHEMSCI.2023.10.5

Abstract

Background: Incidence of perioperative shivering following spinal anesthesia (SA) is 40% to 60% based on current literature. Ketamine in doses between 0.2 to 0.75 mg/kg has been used ... Read More

Acute and Sub-Acute Oral Toxicity Evaluation of Avicularin

Girdhari Lal Gupta; Nikita Patil Samant

Volume 6, Issue 10 , October 2023, , Pages 2327-2337

https://doi.org/10.26655/JMCHEMSCI.2023.10.8

Abstract

Avicularin is a bioactive flavonoid that mainly found in blueberries, American cranberries, apples, and tea. Avicularin isolated from various plants including, Polygonum aviculare, ... Read More

Determining Levels Awareness of Vitamin D as a Silent Epidemic among the Population in Southern Saudi Arabia

Amal A. Abdulbaqi; Rym Hassani; Omaymah Radwan

Volume 6, Issue 10 , October 2023, , Pages 2338-2347

https://doi.org/10.26655/JMCHEMSCI.2023.10.9

Abstract

Vitamin D (VD) is an important nutrient for the human body because it is associated with many diseases. There were many health problems in which vitamin D deficiency had a role, the ... Read More

Predictive Value of Prognostic Nutritional Index in Children with COVID-19

Radhitio Adi Nugroho; Nur Aisiyah Widjaja; Retno Asih Setyoningrum

Volume 6, Issue 10 , October 2023, , Pages 2367-2378

https://doi.org/10.26655/JMCHEMSCI.2023.10.12

Abstract

Background and aim: Severe malnutrition might contribute the poor outcomes in COVID-19. This study aims to investigate the relationship between prognostic nutritional index (PNI) and ... Read More

The Context of Nursing Intervention of Sand Bed Culture in Reducing Osteoarthritis Pain Scale

Syaifurrahman Hidayat; Yuni Sufyanti Arief; Ferry Effendi; Mujib Hannan; Nailiy Huzaimah

Volume 6, Issue 10 , October 2023, , Pages 2387-2396

https://doi.org/10.26655/JMCHEMSCI.2023.10.14

Abstract

Aging causes physiological function to decrease as a result of the aging process. Osteoarthritis is common in the elderly causing chronic pain conditions. The purpose of this study ... Read More

Volume 7 (2024)

Volume 6 (2023)

Volume 5 (2022)

Volume 4 (2021)

Volume 3 (2020)

Volume 2 (2019)

Volume 1 (2018)

Main Subjects = Pharmaceutical sciences

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